Lichen planus
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Atrophic lichen planus
References
Ang Lichen planus (LP) ay isang pangmatagalang kondisyon na nagpapasiklab na kadalasang nakakaapekto sa mga nasa hustong gulang sa kanilang kalagitnaan ng mga taon. Maaari itong lumabas sa balat o mauhog lamad tulad ng bibig, puki, esophagus, voice box, at eye lining. Ang LP ay may iba't ibang anyo depende sa hitsura ng mga pantal at kung saan sila lumilitaw. Iminumungkahi ng mga pag-aaral na ang ilang uri ng LP, tulad ng mga nakakaapekto sa esophagus o mga mata, ay maaaring hindi sapat na masuri. Ang ilang mga anyo ng LP, tulad ng mga hypertrophic at erosive na uri sa bibig, ay maaaring maging partikular na mabigat at magtatagal ng mahabang panahon. Ang iba pang mga salik tulad ng mga gamot o pakikipag-ugnay sa ilang partikular na mga sangkap ay maaaring mag-trigger ng katulad na hitsura ng mga pantal.
Lichen planus (LP) is a chronic inflammatory disorder that most often affects middle-aged adults. LP can involve the skin or mucous membranes including the oral, vulvovaginal, esophageal, laryngeal, and conjunctival mucosa. It has different variants based on the morphology of the lesions and the site of involvement. The literature suggests that certain presentations of the disease such as esophageal or ophthalmological involvement are underdiagnosed. The burden of the disease is higher in some variants including hypertrophic LP and erosive oral LP, which may have a more chronic pattern. LP can significantly affect the quality of life of patients as well. Drugs or contact allergens can cause lichenoid reactions as the main differential diagnosis of LP.
Lichen planus (LP) is a chronic inflammatory disorder that most often affects middle-aged adults. LP can involve the skin or mucous membranes including the oral, vulvovaginal, esophageal, laryngeal, and conjunctival mucosa. It has different variants based on the morphology of the lesions and the site of involvement. The literature suggests that certain presentations of the disease such as esophageal or ophthalmological involvement are underdiagnosed. The burden of the disease is higher in some variants including hypertrophic LP and erosive oral LP, which may have a more chronic pattern. LP can significantly affect the quality of life of patients as well. Drugs or contact allergens can cause lichenoid reactions as the main differential diagnosis of LP.
Ang Lichen planus ay isang kondisyon ng balat na minarkahan ng mga purplish, flat-topped bumps at patch na maaaring magdulot ng matinding pangangati. Ang mga sugat sa balat na ito ay maaaring nakababahala, lalo na kapag malubha ang epekto nito sa bibig o ari. Sa malalang kaso, ang oral lichen planus ay maaaring tumaas pa ang panganib na magkaroon ng isang uri ng kanser sa balat. Maaari rin itong makaapekto sa anit at mga kuko. Habang ang sanhi ng karamihan ng mga kaso ay hindi alam, ang ilan ay maaaring ma-trigger ng ilang mga gamot o impeksyon sa hepatitis C. Karaniwang kinasasangkutan ng paggamot ang mga matatapang na cream para sa mga naisalokal na kaso at mga oral steroid para sa mga mas laganap.
Lichen planus is a skin condition marked by purplish, flat-topped bumps and patches that can cause intense itching. These skin lesions can be distressing, especially when they affect the mouth or genitals severely. In severe cases, oral lichen planus may even increase the risk of developing a type of skin cancer. It can also affect the scalp and nails. While the cause of most cases is unknown, some may be triggered by certain medications or hepatitis C infection. Treatment typically involves strong creams for localized cases and oral steroids for more widespread ones.
Lichen planus is a skin condition marked by purplish, flat-topped bumps and patches that can cause intense itching. These skin lesions can be distressing, especially when they affect the mouth or genitals severely. In severe cases, oral lichen planus may even increase the risk of developing a type of skin cancer. It can also affect the scalp and nails. While the cause of most cases is unknown, some may be triggered by certain medications or hepatitis C infection. Treatment typically involves strong creams for localized cases and oral steroids for more widespread ones.
Ang Lichen planus ay isang kondisyon kung saan nagdudulot ng pamamaga ang immune system, na nagreresulta sa mga natatanging marka sa balat at mucous membrane. Nakakaapekto ito sa humigit-kumulang 5% ng mga nasa hustong gulang, mas madalas sa mga babae, at kadalasang nagsisimula sa edad na nasa katanghaliang gulang. Ang paglahok sa bibig ay nakikita sa hanggang 77% ng mga kaso, kadalasang nakakaapekto sa panloob na pisngi. Bagama't ang ilang tao ay maaaring walang anumang sintomas, ang iba ay maaaring makaranas ng pananakit at magkaroon ng problema sa ilang partikular na pagkain (hal. , acidic, maanghang) o toothpaste.
Lichen planus is an immune-mediated inflammatory condition leading to characteristic lesions on skin and mucous membranes. It presents in up to 5% of the general adult population with a female predilection (2:1); the onset is most commonly in middle age. Up to 77% of patients with lichen planus have oral disease, with buccal mucosa the most common subsite. The oral lesions may be asymptomatic, although a subset of patients have pain and difficulty tolerating certain foods (e.g., acidic, spicy) and toothpaste.
Lichen planus is an immune-mediated inflammatory condition leading to characteristic lesions on skin and mucous membranes. It presents in up to 5% of the general adult population with a female predilection (2:1); the onset is most commonly in middle age. Up to 77% of patients with lichen planus have oral disease, with buccal mucosa the most common subsite. The oral lesions may be asymptomatic, although a subset of patients have pain and difficulty tolerating certain foods (e.g., acidic, spicy) and toothpaste.
Upang kumpirmahin ang diagnosis ng cutaneous lichen planus, maaaring gawin ang isang biopsy sa balat. Ang direktang immunofluorescence (DIF) ay maaaring maging kapaki-pakinabang sa mga pasyenteng may bullous lesions upang maiba ang kondisyon mula sa isang autoimmune vesiculobullous na sakit.